Molecular Convergence of Neurodevelopmental Disorders
نویسندگان
چکیده
منابع مشابه
Neurodevelopmental Disorders
The effective identification of neurodevelopmental disorders is essential for early diagnosis and provision of intervention services. For many of these conditions, one of the primary domains of abnormality is language development. This review addresses what is known about the earliest indicators of language impairment across a range of neurodevelopmental disorders; consideration is given to bot...
متن کاملMolecular Genetic Investigation of Autosomal Recessive Neurodevelopmental Disorders
Development of the human brain occurs in a number of complex preand postnatal stages which are governed by both genetic and environmental factors. Aberrant brain development due to inherited defects may result in a wide spectrum of neurological disorders which are commonly encountered in the clinical field of paediatric neurology. In the work for this thesis, I have investigated the molecular b...
متن کاملMolecular mechanisms underlying neurodevelopmental disorders, ADHD and autism.
Neurodevelopmental disorders such as attention deficit hyperactivity disorder and autism represent a significant economic burden, which justify vigorous research to uncover its genetics and developmental clinics for a diagnostic workup. The urgency of addressing attention deficit hyperactivity disorder comorbidities is seen in the chilling fact that attention deficit hyperactivity disorder (ADH...
متن کاملCNVs in neurodevelopmental disorders
Copy number variations (CNVs) consist of duplications or deletions of chromosomal regions ranging from a few hundred to more than a million bases in size, and are likely to play a role in phenotypic diversity and evolution. Recent advances in the identification and mapping of CNVs among normal individuals and in model systems, using bioinformatics and hybridization-based methods, are beginning ...
متن کاملSleep and neurodevelopmental disorders.
Sleep disorders in children are among the most common parental complaints to health care professionals and frequently occur in children with neurological and developmental disorders. Thus, I am grateful to the editors of Neuropediatrics for the opportunity to assemble in one place several papers that outline the contemporary knowledge about sleep disorders in patients with neurodevelopmental di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2014
ISSN: 0002-9297
DOI: 10.1016/j.ajhg.2014.09.013